25-30 August 2019
Henry Ford Building
Europe/Berlin timezone

Accelerated and sensitivity improved temperature-swept pure-shift NMR

Not scheduled
4h
Harnack House and Henry Ford Building

Harnack House and Henry Ford Building

Board: 397
Poster Solution NMR development and applications Posters

Speaker

Ms Małgorzata Rytel (Centre of New Technologies, University of Warsaw, Banacha 2C, 02-093 Warsaw, Poland )

Description

There exists a number of experimental methods which provide homodecoupled (pure-shift) 1H NMR spectra. Standard techniques (like PSYCHE [2] and TSE-PSYCHE [3]) require to record spectra in a pseudo-2D mode where chunks of data are acquired as separate FIDs. However, this often leads to very time-consuming experiments [1]. The problem with time rises, when a series of pure-shift proton spectra needs to be measured under different conditions, such as temperature, pH, pressure, concentration of compound in a sample, etc.

We present two different improvements using Radon transformation in post-processing [4, 5]. The first one may be used to boost sensitivity and resolutionn in series of pure-shift spectra. In a second technique we obtain a series of pure-shift spectra in shorter time. The idea is to measure only one chunk of data per experiment and process the data with modified version of Radon transformation. Additionally, our method allows to decode rates of linear changes of peaks positions caused by variations of conditions mentioned earlier.

References:
[1] K. Zangger, Prog. Nucl. Macn. Resonance, 86-87 (2014), 1-2015
[2] M. Foroozandeh, R. W. Adams, N. J. Meharry, D. Jeannerat, M. Nilsson and G. A. Morris, Angew. Chem., Int. Ed., (2014), 53, 6990–6992
[3] M. Foroozandeh , R. W. Adams , P. Kiraly , M. Nilsson and G. A. Morris, Chem. Commun., (2015), 51 , 15410 -15413
[4] R. Dass, P. Kasprzak, K. Kazimierczuk, J. Magn. Reson. (2017), 282, 114
[5] . E. Kupče, R. Freeman, Concepts Magn. Reson., 22A (2004), 4-11

Primary authors

Ms Małgorzata Rytel (Centre of New Technologies, University of Warsaw, Banacha 2C, 02-093 Warsaw, Poland ) Dr Paweł Kasprzak (Department of Mathematical Methods in Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-903 Warsaw, Poland and Centre of New Technologies, University of Warsaw, Banacha 2C, 02-097 Warsaw, Poland ) Dr Piotr Setny (Centre of New Technologies, University of Warsaw, Banacha 2C, 02-097 Warsaw, Poland ) Dr Krzysztof Kazimierczuk (Centre of New Technologies, University of Warsaw, Banacha 2C, 02-097 Warsaw, Poland )

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