25-30 August 2019
Henry Ford Building
Europe/Berlin timezone

Developments of NMR for Applications in Chemical Engineering and Medicine

30 Aug 2019, 10:30
35m
Lecture Hall B (Henry Ford Building)

Lecture Hall B

Henry Ford Building

Invited talk MRI developments and applications MRI Developments

Speaker

Prof. Petrik Galvosas (MacDiamid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University Wellington)

Description

To enable wider application of NMR/MRI technologies in science, engineering and medicine, approaches must be specialised, accessible, simple and affordable. In this context this lecture will give recent examples from our journey of pushing MR boundaries.

We will report on the parallel acquisition of q-space, thus enabling real time monitoring of averaged propagators [1]. We will also discuss Magnetic Resonance Pore Imaging (MRPI) at resolutions well beyond the limits of conventional MRI [2] and demonstrate how recent advances in Rheo-NMR enable further insight into complex fluids under shear [3].

With respect to medical applications the lecture will report on measuring averaged fractional anisotropy [4], discuss options for the measurement of bone-to-total-volume ratios [5], metabolic rates of cells under mechanical stress and developments towards sensors for blood oxygenation [6].

To expand NMR and MRI into non-conventional areas as highlighted above it is necessary to develop affordable electronics [7] which meets the requirements of purpose built MR systems. Furthermore, experimental protocols and data analysis are required to be robust, especially under conditions of low signal to noise ratios [8,9]. Together with appropriate magnet systems we see great potential of NMR and MRI to be used in process control, quality assurance, point of care sensors as well as in academic and industrial research.

[1] Kittler, W. et al., Phys. Rev. E 92 023016 (2015).
[2] Hertel, S. A. et al., Phys. Rev. E 92 012808 (2015).
[3] Galvosas, P, et al., Magn. Reson. Chem.. Doi:/10.1002/mrc.4861 (2019).
[4] Zong, F. et al., Magn. Reson. Chem. 55 498-507 (2017).
[5] Brizi, L. et al., Magn. Reson. Med. 79 (2018).
[6] Thomas, D., Victoria University of Wellington, Hdl:123456789/3. Web. (2018).
[7] Ang, A. et al., Proceeding ISMRM-ESMRMB 16-21 June 2018 Paris, France.
[8] Teal, P. D. and C. Eccles, Inverse Problems 31 045010 (2015).
[9] Anjum, A. R. et al., Mag. Res. Chem. 56 740-747 (2018).

Primary authors

Dr Robin Dykstra (School of Engineering and Computer Science, Victoria University of Wellington) Dr Sergei Obruchkov (Robinson Research Institute, Victoria University of Wellington) Dr Mark Hunter (Robinson Research Institute, Victoria University of Wellington) Prof. Paul Teal (School of Engineering and Computer Science, Victoria University of Wellington) Prof. Yu-Chieh Tzeng (Department of Surgery & Anaesthesia, University of Otago) Prof. Petrik Galvosas (MacDiamid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University Wellington)

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