My adventures with NMR started in 1973 at the Technical University in Berlin with a just-for-fun project on a 90 MHz ‘high-field‘ Fourier NMR spectrometer [1]. Fun and curiosity has been my main driver since to explore different measurement NMR methodologies along with novel applications. Building on experience with spectroscopy of liquids and solids in homogeneous fields, insights into...
SABRE, a method pioneered about a decade ago, uses parahydrogen and reversible exchange in solution to hyperpolarize organic molecules. In recent years this method has been adapted to polarize heteroatoms such as 15N, rapidly (in seconds) on several hundred different molecules, with an apparatus that can be built for about 1% of the cost a DNP system. Two different strategies have been...
The world-wide diabetes pandemic has heightened the need for early screening and prevention. Type 2 diabetes develops slowly and insidiously, and the early stages are often undetected. Here we describe how NMR relaxometry using small table-top devices can be used for the early detection of insulin resistance and metabolic syndrome. These conditions affect nearly one half of US adults and...
Ancient mummies and bones, paintings and violins – what do they have in common? First, they are all highly relevant to cultural heritage, and second, we can use mobile NMR to learn specific details about each of them.
Mobile NMR is a non-destructive technique that uses single-sided mobile NMR sensors capable of recording NMR signals from samples that are exterior to the magnet. The two main...
Recently, spin-exchange relaxation free (SERF) alkali-vapor magnetometers have been applied as detectors of nuclear magnetic resonance (NMR) in the zero to ultralow field (ZULF) regime [1]. In ZULF the reduction of spectral line broadening due to field gradients as well as the possible existence of long-lived coherences [2] may lead to spectra with high resolution. These can provide new...